The Gomberg-Bachmann reaction for the arylation of anilines with aryl diazotates.
نویسندگان
چکیده
Simply aqueous sodium hydroxide is sufficient to exclude ionic side reactions and to prepare 2-aminobiphenyls from aryl diazotates and anilines through a new variant of the Gomberg-Bachmann reaction (see scheme). The metal-free reaction under basic conditions allows to exploit the highly radical-stabilizing effect of the aniline's free amino function for the first time, which leads to a so far unreached regioselectivity.
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ورودعنوان ژورنال:
- Chemistry
دوره 18 37 شماره
صفحات -
تاریخ انتشار 2012